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Akkermansia muciniphila
Akkermansia muciniphila: paradigm for next-generation beneficial microorganisms. Cani PD, Depommier C, Derrien M, Everard A, de Vos WM. Nat Rev Gastroenterol Hepatol. 2022 Oct;19(10):625-637.
Akkermansia muciniphila Reduces Peritonitis and Improves Intestinal Tissue Wound Healing after a Colonic Transmural Defect by a MyD88-Dependent Mechanism. Bachmann R, Van Hul M, Baldin P, Léonard D, Delzenne NM, Belzer C, Ouwerkerk JP, Repsilber D, Rangel I, Kartheuser A, Brummer RJ, De Vos WM, Cani PD. Cells. 2022 Aug 27;11(17):2666. doi: 10.3390/cells11172666.
Food Reward Alterations during Obesity Are Associated with Inflammation in the Striatum in Mice: Beneficial Effects of Akkermansia muciniphila. Huwart SJP, de Wouters d’Oplinter A, Rastelli M, Van Hul M, de Vos WM, Luquet S, Cani PD, Everard A. Cells. 2022 Aug 16;11(16):2534.
Comparative Genomics and Physiology of Akkermansia muciniphila Isolates from Human Intestine Reveal Specialized Mucosal Adaptation. Ouwerkerk JP, Tytgat HLP, Elzinga J, Koehorst J, Van den Abbeele P, Henrissat B, Gueimonde M, Cani PD, Van de Wiele T, Belzer C, de Vos WM. Microorganisms. 2022 Aug 9;10(8):1605.
Serum metabolite profiling yields insights into health promoting effect of Akkermansia muciniphila in human volunteers with a metabolic syndrome. Depommier C, Everard A, Druart C, Maiter D, Thissen JP, Loumaye A, Hermans MP, Delzenne NM, de Vos WM, Cani PD. Gut Microbes. 2021 Jan-Dec;13(1):1994270. doi: 10.1080/19490976.2021.1994270.
Beneficial Effects of Akkermansia muciniphilaAre Not Associated with Major Changes in the Circulating Endocannabinoidome but Linked to Higher Mono-Palmitoyl-Glycerol Levels as New PPARα Agonists. Depommier C, Vitale RM, Iannotti FA, Silvestri C, Flamand N, Druart C, Everard A, Pelicaen R, Maiter D, Thissen JP, Loumaye A, Hermans MP, Delzenne NM, de Vos WM, Di Marzo V, Cani PD. Cells. 2021 Jan 19;10(1):185. doi: 10.3390/cells10010185.
Toxicological safety evaluation of pasteurized Akkermansia muciniphila. Druart C, Plovier H, Van Hul M, Brient A, Phipps KR, de Vos WM, Cani PD. J Appl Toxicol. Feb;41(2):276-290. doi: 10.1002/jat.4044.
Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice. Depommier C, Van Hul M, Everard A, Delzenne NM, De Vos WM, Cani PD. Gut Microbes. 2020 Sep 2;11(5):1231-1245.
Supplementation with Akkermansia muciniphila in overweight and obese human volunteers: a proof-of-concept exploratory study. Depommier C, Everard A, Druart C, Plovier H, Van Hul M, Vieira-Silva S, Falony G, Raes J, Maiter D, Delzenne NM, de Barsy M, Loumaye A, Hermans MP, Thissen JP, de Vos WM, Cani PD. Nature Medicine. 2019 Jul;25(7):1096-1103. doi: 10.1038/s41591-019-0495-2. Epub 2019 Jul 1.
A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice. Plovier H, Everard A, Druart C, Depommier C, Van Hul M, Geurts L, Chilloux J, Ottman N, Duparc T, Lichtenstein L, Myridakis A, Delzenne NM, Klievink J, Bhattacharjee A, van der Ark KC, Aalvink S, Martinez LO, Dumas ME, Maiter D, Loumaye A, Hermans MP, Thissen JP, Belzer C, de Vos WM, Cani PD. Nature Medicine. 2017 Jan;23(1):107-113. doi: 10.1038/nm.4236. Epub 2016 Nov 28.
